GLP-1 action in the mouse bed nucleus of the stria terminalis

GLP-1 action in the mouse bed nucleus of the stria terminalis

Glucagon-like peptide-1 (GLP-1) injected into the brain reduces food intake. Similarly, activation of preproglucagon (PPG) cells in the hindbrain which synthesize GLP-1, reduces food intake. However, it is far from clear whether this happens because of satiety, nausea, reduced reward, or even stress. Here we explore the role of the bed nucleus of the stria terminalis (BNST), an area involved in...

Glutaminergic receptor in the rostroal ventrolateral medulla mediate the cardiovascular responses to activation of the bed nucleus of the stria terminalis in female ovariectomized rat

Introduction: Experiments were done to investigate the cardiovascular response to glutamate (Glu) injection in the bed nucleus of stria terminalis (BST) in urethane anesthetized ovariectomized (OVX) or OVX estrogen  treated (OVX+E)  female Wistar rats. In this study also the effect of glutaminergic system of the rostral ventrolateral medulla (RVLM) on Glu stimulation of cardiovascular...

اثرات داروهای هیستامینرژیک در bed nucleus of the stria terminalis (bnst) رت ها در تست elevated plus maze بر رفتارهای شبه اضطرابی

سیستم هیستامینرژیک مرکزی دارای تاثیرات تنظیمی بر رفتارهای شبه اضطرابی هم در حیوانات و هم در انسان است. این تاثیرات از طریق رسپتور h1 و h2 میانجیگری میشود. تست epm(elevatd plus-maze( برای بررسی تاثیرات اضطراب زایی یا اضطراب زدایی داروها در جوندگان بکار میرود. شواهد نشان می دهند که فعالیت (bnst) bed nucleus the stria terminalis رفتار شبه اضطرابی را در انسانها و حیوانات تنظیم می کند. در مطالعه حاض...

Intrinsic connections in the anterior part of the bed nucleus of the stria terminalis.

Intrinsic connections in the anterior portion of the bed nucleus of the stria terminalis (BNST-A) were studied using patch recordings and ultraviolet (UV) glutamate uncaging (GU) in vitro. UV light was delivered at small BNST-A sites in a grid-like pattern while evoked responses were monitored in different BNST-A regions. Three sectors were distinguished in the BNST-A using fiber bundles readil...

The role of the bed nucleus of the stria terminalis in learning to fear.